ABSTRACT
The pathogenesis of overactive bladder syndrome (OAB) is still unclear.Although OAB is defined as " overactive bladder" , the lesion is not confined to the bladder, studies have been showed that urethral instability (URI) can also induce symptom of OAB.The author has observed 146 children with OAB and found that URI is one of the causes of OAB, and also has a significant effect on the treatment of OAB.Recently, the role of URI played in OAB has gradually been emphasized, however, the research of URI is still controversial.At present, the first-line treatment of OAB is mainly anticholinergic drugs for the detrusor overactivity, and lack of diagnosis and related treatment mea-sures in urethral dysfunction.The updated progress of URI in children with OAB were summarized in this review.
ABSTRACT
The pathogenesis of overactive bladder syndrome (OAB) is still unclear.Although OAB is defined as "overactive bladder",the lesion is not confined to the bladder,studies have been showed that urethral instability (URI) can also induce symptom of OAB.The author has observed 146 children with OAB and found that URI is one of the causes of OAB,and also has a significant effect on the treatment of OAB.Recently,the role of URI played in OAB has gradually been emphasized,however,the research of URI is still controversial.At present,the first-line treatment of OAB is mainly anticholinergic drugs for the detrusor overactivity,and lack of diagnosis and related treatment measures in urethral dysfunction.The updated progress of URI in children with OAB were summarized in this review.